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[Bats, viruses and humans: coronaviruses on the rise?].

Identifieur interne : 006693 ( Main/Exploration ); précédent : 006692; suivant : 006694

[Bats, viruses and humans: coronaviruses on the rise?].

Auteurs : Christine Winter [Allemagne] ; Georg Herrler

Source :

RBID : pubmed:24511826

Descripteurs français

English descriptors

Abstract

The outbreak of the SARS coronavirus in 2002/2003 and the recent disease cases with a new human coronavirus (originally designated EMC-CoV, recently renamed MERS-CoV) have put the focus onto the virus family Coronaviridae. Both viruses appeared to have managed to jump over the species barrier from a bat reservoir to the human population. Bats are considered to serve as a natural reservoir for coronaviruses infecting mammals. An important factor for crossing the species-barrier is the adaptation to a new receptor on cells of the new host species. During evolution coronaviruses have developed a large diversity of binding specificities demonstrating the high flexibility of the coronaviral spike protein, which is responsible for binding to target cells.

PubMed: 24511826


Affiliations:


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Le document en format XML

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