[Bats, viruses and humans: coronaviruses on the rise?].
Identifieur interne : 006693 ( Main/Exploration ); précédent : 006692; suivant : 006694[Bats, viruses and humans: coronaviruses on the rise?].
Auteurs : Christine Winter [Allemagne] ; Georg HerrlerSource :
- Berliner und Munchener tierarztliche Wochenschrift [ 0005-9366 ]
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Glycoprotéine de spicule des coronavirus.
- physiologie : Coronaviridae.
- virologie : Chiroptera, Réservoirs d'agents pathogènes.
- épidémiologie : Infections à Coronaviridae.
- Animaux, Humains.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Spike Glycoprotein, Coronavirus.
- epidemiology : Coronaviridae Infections.
- physiology : Coronaviridae.
- transmission : Coronaviridae Infections.
- virology : Chiroptera, Disease Reservoirs.
- Animals, Humans.
Abstract
The outbreak of the SARS coronavirus in 2002/2003 and the recent disease cases with a new human coronavirus (originally designated EMC-CoV, recently renamed MERS-CoV) have put the focus onto the virus family Coronaviridae. Both viruses appeared to have managed to jump over the species barrier from a bat reservoir to the human population. Bats are considered to serve as a natural reservoir for coronaviruses infecting mammals. An important factor for crossing the species-barrier is the adaptation to a new receptor on cells of the new host species. During evolution coronaviruses have developed a large diversity of binding specificities demonstrating the high flexibility of the coronaviral spike protein, which is responsible for binding to target cells.
PubMed: 24511826
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001051
- to stream PubMed, to step Curation: 001051
- to stream PubMed, to step Checkpoint: 003479
- to stream Ncbi, to step Merge: 002827
- to stream Ncbi, to step Curation: 002827
- to stream Ncbi, to step Checkpoint: 002827
- to stream Main, to step Merge: 006C11
- to stream Main, to step Curation: 006693
Le document en format XML
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<term>Infections à Coronaviridae (épidémiologie)</term>
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<front><div type="abstract" xml:lang="en">The outbreak of the SARS coronavirus in 2002/2003 and the recent disease cases with a new human coronavirus (originally designated EMC-CoV, recently renamed MERS-CoV) have put the focus onto the virus family Coronaviridae. Both viruses appeared to have managed to jump over the species barrier from a bat reservoir to the human population. Bats are considered to serve as a natural reservoir for coronaviruses infecting mammals. An important factor for crossing the species-barrier is the adaptation to a new receptor on cells of the new host species. During evolution coronaviruses have developed a large diversity of binding specificities demonstrating the high flexibility of the coronaviral spike protein, which is responsible for binding to target cells.</div>
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